Chemical purification processes often require a fraction collection step. The collected fractions, in some cases multiple, often need to be split up into different formats and volumes for a wide variation of down stream processing. In 2005, Labman Automation supplied a reformatting system for a company based in the UK with a requirement to purify a compound library containing 5 million samples!

The system, based on a two-armed Tecan RSP loads incoming tubes containing dried fractions into a dissolution unit, re-suspends each fraction with the selected solvent then re-constitutes the dissolved fractions (some multiple) into the required output format.